PPIs are not interchangeable. Prescription PPIs and OTC PPIs may differ in dose, indication, duration, efficacy, and directions for use. Use Prilosec OTC as directed for 14 days to treat frequent heartburn. Do not take for more than 14 days or more often than every four months unless directed by a doctor. All patients should talk to their doctor before stopping or starting any medication therapy. Prilosec OTC contains omeprazole-Mg 20.6 mg, equivalent to omeprazole 20 mg, which is the leading dose strength for prescription omeprazole (Prilosec).
Some prescription plans changed as of January 1, 2011. Some
plans will limit coverage of certain branded prescription PPIs or will increase
the co-pay. For frequent heartburn patients who have cost concerns, consider recommending
prescription strength Prilosec OTC† as an effective and affordable acid
reducer available over-the-counter.
As you can see in the table above, the average co-pay per day for a branded Rx PPI
is higher than the average cost per day of Prilosec OTC. In most cases, the costs
are significantly higher.
With Prilosec OTC, your patients may be able to save some money and still get effective
treatment for their frequent heartburn.
† Use as directed for 14 days to treat frequent heartburn. Do not take
for more than 14 days or more often than every 4 months unless directed by a doctor.
Not for immediate relief. Prilosec OTC contains omeprazole-Mg 20.6 mg, equivalent
to omeprazole 20 mg, which is the leading dose strength for prescription omeprazole
1 Wolters Kluwer Pharma Solutions, Dynamic Claims, [Employer Groups JFM 2011]. The comparison of PPIs is a general reference only.
2 Co-pay cost per day calculated as monthly prescription PPI co-pay divided
by 30 days.
3 P&G calculation based in part on non-promoted and promoted weighted
unit price for 14ct, 28ct, and 42ct, reported by The Nielsen Company in the U.S.
market for the Stomach Remedies Category for the period latest week ending September
All trademarks above are the property of their respective owners and are used for
illustration purposes only.
* Wolters Kluwer: OTC Acid Reducer Category.
** Based on Pharmacy Times 2010 survey.